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ChemoCentryx, a pharmaceutical company located in Mountain View, CA, seeks highly motivated professionals to join our team.

All ChemoCentryx employees share the rewards of their work through a generous stock option program. We also offer 401K and Flexible Spending Accounts, and a comprehensive benefits package, including medical, dental and vision coverage and life and long-term disability insurance.

Please email your resume & cover letter to: hiring@chemocentryx.com or FAX to: (650) 210-2910. No phone calls please. EOE


Administrative Assistant/Senior Administrative Assistant

Administrative Assistant/Senior Administrative Assistant will provide administrative support to the Chief Financial Officer (CFO), Chief Medical Officer (CMO) and the Senior Vice President of Research.

Duties

  • Set up meetings/activities via Outlook, draft/change/format documents using MS Word of MS Excel, prepare presentations using PowerPoint, answer calls, file documents and process mail/correspondence.
  • Arrange and coordinate onsite and offsite executive meetings.
  • Make travel arrangements in accordance with preferences, prepare trip folders and prepare travel and expense reports for charges on corporate credit card.
  • Prepare, coordinate and distribute quarterly board committee packages. Provide assistance with preparation of board packages. Ensure directors' travel arrangements are secured and coordinated. Maintain attendance records of board and committee meetings and assist the CFO in the scheduling of board and committee meetings and conference calls. Arrange catering and other requirements associated with board meetings.
  • Provide assistance in maintaining a complete and accurate corporate minutes book. Ensure the timely execution by Secretary of approved board and committee minutes. Ensure minutes book is up-to-date to include all minutes, consents and other written actions taken by the board, committees and stockholders. Assist the CFO in the coordination of the annual stockholders meeting.
  • Maintain files of all stock options grants and related activities. Ensure the timely distribution and return receipt of stock option agreements. Provide support to stock option administration, as appropriate.
  • Ensure files for all directors and officers are maintained and complete (e.g. Section 16 filings, D&O questionnaires, etc.).
  • Corporate phone support during the Receptionist's lunch and rest breaks.
  • Perform special projects as requested.

Qualifications

  • HS Diploma or equivalent 3 to 5 years of administrative support, preferably in biotechnology or technology.
  • Extremely professional with excellent written and verbal communication skills.
  • Attention to detail and follow through.
  • Time management, flexibility and organizational skills. Ability to multi-task and effectively prioritize in a dynamic and fast-paced environment.
  • Ability to work with confidential information in an appropriate manner and use discretion in communications.
  • Demonstrated team and collaborative work with other administrative staff.
  • Proficiency with MS Office (Word, PowerPoint and Excel) and Outlook.

Reference Job Code: #030

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Director - Human Resources

Seeking Human Resources Director to manage the planning and implementation of HR strategies, programs, and initiatives to support the achievement of the company's short and long-term business objectives.

Some of the Key Responsibilities

  • Partners with managers and senior management in all matters concerning Human Resources and People Management
  • Develops annual HR Strategic Plan in conjunction with senior management
  • Drives delivery of HR programs into the organization, including talent acquisition, staffing and selection, employment onboarding, compensation, training and development, talent management and succession planning, employee relations, AA/EEO compliance, and retention
  • Helps to drive organizational effectiveness through Performance Management processes; improves manager and employee performance by identifying problems; evaluating, and implementing recommended solutions; coaching and counseling managers and employees. Assists with the delivery of training when needed
  • Consults with department heads & senior management on organizational structures that will support and enable talent management, employee development, and building of capabilities to support the company's vision and strategic goals

Requirements

  • Ability to foster a positive team environment and build trusting relationships with employees
  • Track record of success in achieving results
  • Demonstrated success providing direct, complete, and actionable corrective feedback
  • Effective communicator -- strong presentation and public speaking skills; able to write clear and succinct messages for a myriad of purposes and audiences
  • Comfortable in fast-paced and dynamic organizations
  • Experience in employee relations and performance management

Education and Experience

Bachelor's degree or equivalent, plus a minimum of 10 years progressively responsible HR experience. Experience in the Biopharmaceutical Industry highly desired.

Reference Job Code: CCX #017

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Director/Senior Director, Biology

The Director/Senior Director, Biology will report to the Senior Vice President of Research. This life sciences research leader will participate in strategic development and implementation of early and late stage research programs while identifying new targets to ensure that a robust pipeline of product candidates is moving towards the clinic. This person will work closely with the members of the executive team and provide both strategic and day-to-day guidance to the scientific team.

  • Initiate and advance new discovery programs to the clinical stage
  • Lead and manage research activities of the biology staff
  • Provide key support to the clinical group in the areas of biomarker development and mechanism of action/translational studies
  • Implement and supervise all necessary screening, preclinical MOA, and pharmacology studies (both in vitro and in vivo) to support the filing of INDs

Requirements

  • Ph.D. in Biology, Immunology, or related field
  • 10+ years of industry experience in small molecule drug discovery/development, with at least 5 years in a leadership role
  • Evidence of scientific leadership with publication in top-tier journals
  • A successful track record of advancing multiple product candidates from discovery to the clinic, with lead responsibilities
  • Highly-motivated to rapidly accomplish goals
  • Demonstrated expertise and understanding of all aspects of small molecule discovery and early development, including: target identification and validation, development of screening strategies, cell biology and immunology, in vitro and in vivo assay/model development, PK/PD, and ADME.
  • Prior experience in auto-immune and/or inflammation research is preferred and oncology expertise desired
  • A passion for (and commitment to) discovering and developing transformative, best in class therapeutics
  • Exceptional leadership qualities, with the strong management skills necessary to oversee and grow a first class, results oriented discovery and early development team

Education and Experience

Bachelor's degree or equivalent, plus a minimum of 10 years progressively responsible HR experience. Experience in the Biopharmaceutical Industry highly desired.

Reference Job Code: CCX #028

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Medical Director

This Medical Director level position requires the ability to work independently, with appropriate supervision, in responsibilities associated with all aspects of design, setup, monitoring, and analysis of Phase 1 - 3 clinical trials. This person must have excellent analytical and communication skills, and the ability to interact effectively with other members of the department, as well as with study investigators and their staff, CROs and vendors operating on behalf of ChemoCentryx. The individual also needs to be involved in other duties in the department including strategic planning, clinical plan development, potential partnering discussions, regulatory meetings, departmental meetings, planning and preparation for scientific meetings, staff training, and patient recruitment initiatives.

Responsibilities

  • Co-lead the C5aR (CCX168) and CCR2 (CCX140-B and CCX872-B) clinical development programs in renal diseases (often in orphan disease settings) and cancer; as such, participate in investigator outreach activities, design, placement, execution, data analysis, and report writing for the clinical trials, including Phase 1 through Phase 3 clinical trials.
  • Medical monitoring and regular safety review of active clinical trials.
  • Lead specific clinical trials, e.g., CCX168 Phase 1 and later stage clinical trials.
  • Attend scientific meetings on behalf of CCXI to meet with investigators and key opinion leaders, submit and present abstracts.
  • Organize and lead scientific advisory board meetings.
  • Be actively involved in planning and preparation of Regulatory meetings and submissions, e.g., CCX168 End-of-Phase 2 meeting.
  • Help mentor and guide other Department members.
  • Participation in generation and critical review of study-related documents including study protocols, protocol amendments, investigator brochures, monitoring plans, informed consent documents, and CRFs.
  • Includes travel up to 30% at times.

Education & Experience

  • Requires an MD with a minimum of 5 year of industry experience.
  • Experience in one or more of the following area(s): Oncology, nephrology, and rheumatology desirable.
  • Prior training and experience with Good Clinical Practices (GCPs).
  • Excellent verbal and written skills along with the ability to work collaboratively in a dynamic and creative environment.
  • Ability to critically analyze and evaluate information/data and generate an appropriate action plan in a timely manner
  • Track record of creativity, high performance, and demonstrated ability to work independently and meet deadlines.
  • Ability to inspire and motivate others to achieve the corporate goals
  • Exhibits initiative, is proactive and able to contribute to overall medical and clinical development activities.
  • This position requires attention to detail and the ability to interact effectively with other staff.

Reference Job Code: CCX #032

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On-Call Consulting Graphic Artist

This is a part-time on-call position. Must be available at least several times year to work 1 day to 1 week at a time.

The Consulting Graphic Artist will support all tiers of research and development staff and management in preparing effective scientific presentations, posters and publications. This includes, but is not limited to:

  • Directly supporting research and development presentation projects, with the ability to:
  • Plot simple graphs
  • Devise unique diagrams and illustrations
  • Produce artwork appropriate for major publications such as Science, Nature, etc.
  • Convert to/create high resolution images and improve the clarity of existing graphics when possible
  • Assist in translating scientific concepts and large data sets into complex scientific figures and illustrations.
  • Anticipate and troubleshoot production obstacles to ensure timely delivery of work.

Required Skills and Experience

  • Demonstrated competency and expertise with Adobe in-Design, PowerPoint, GraphPad Prism and MS Office.
  • Extreme attention to detail and ability to ensure quality and accuracy in all information being presented.
  • Adept at time and project management - able to effectively communicate deadlines
  • Possess and demonstrate both a creative and technical ability to design and deliver information.
  • Comfortable working with scientists and cross functional teams.
  • Demonstrated experience providing graphic design and presentation support in a life science research and development environment.
  • At least five (5) years of experience in providing graphic design, and presentation support.

Education Minimum Requirement

  • High School Diploma or GED required.
  • A Bachelor's degree in graphic design or a related field is preferred, but not required.

Reference Job Code: OCCGA

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Patent Agent / Associate Patent Attorney

Flexible Title - commensurate with the candidate's background and experience

Duties and Responsibilities

  • Prepare, file and prosecute U.S. and foreign patent (mainly chemistry) applications
  • Conduct patentability, technology assessments, and clearance searches in areas which may impact the Company's intellectual property
  • Support business development efforts, including IP due diligence for prospective opportunities
  • Keep management informed of competitive intellectual property developments and relevant business advice, including worldwide patent prosecution updates as they affect the company's business or opportunities
  • Conduct patent application review meetings with inventors
  • Review responses to US and ex-US Patent Office examination communications drafted by outside patent counsel
  • Manage outside patent counsel activities and interactions
  • Process invention assignments and declarations
  • Review and execute material transfer agreements, confidentiality disclosure agreements, technology transfer agreements and other legal instruments such as contracts
  • Manage external collaborations
  • Review ongoing scientific developments by the Company's research and development teams
  • Review abstracts, posters and publications prepared by the Company's research and development teams prior to submission

Education & Experience

  • Bachelor of Science degree in Chemistry (organic/medicinal) or Biochemistry
  • Minimum of 5 years of professional experience in preparation and prosecution of chemistry (mainly small molecules) and biochemistry/biology patent applications
  • At least 3 years of which were spent as a patent agent or in a related role(s) within a biotechnology, pharmaceutical or related industry
  • Admission to USPTO as a Patent Agent required
  • Demonstrated knowledge of the domestic and international laws, regulations, and processes relating to chemistry (mainly) and biochemistry/biology patents and applications
  • Knowledge of the standard concepts, practices, and procedures of the patent agent function within a pharmaceutical or related industry
  • Experience using IP software and systems such as ChemDraw, USPTO website, web-based scientific research applications such as SciFinder and docketing, research database and other relevant software
  • Effective communicator in both oral and written forms
  • Capable of high performance in independent work as well as in team setting

Reference Job Code: #022

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Scientist - Principal Scientist, Clinical Biomarker Specialist

We currently seek a Scientist to join our Clinical Development Group. The position requires a Ph.D. in Immunology, Cancer Biology or related field, with a minimum of 7 years of experience within the Pharmaceutical/Biotechnology sector. The title is flexible (Scientist - Principal Scientist) and will be commensurate with the candidate's background and experience.

The Scientist is responsible for developing and implementing the strategic and tactical aspects of biomarker assays performed in our clinical trials. This individual will work cross-functionally within the team and ChemoCentryx, as well as outside consultants and vendors to help formulate and implement the plan for each clinical trial. The major focus of this position will be coordinating the biomarker evaluation of novel therapeutic agents and development of target engagement and biomarker assays that will support the drug discovery efforts of the therapeutic area. Additional responsibilities include the identification and validation of novel disease pathways and biomarkers.

  • Actively participate in and lead the development and implementation of biomarker strategies for individual projects
  • Manage the development, outsourcing and validation of clinically applicable biomarker assays including pharmacodynamic, predictive, prognostic, safety and other biomarkers
  • Oversee biomarker and complex data analysis; closely works with multiple departments to ensure complete and precise implementation of biomarker strategies
  • Identify, review and select CROs that can support the initiatives and are capable of delivering quality results on time
  • Ensure that overall budgets, schedules and performance standards at CROs meet specifications
  • Facilitate and provide the management oversight of new and ongoing studies in-house and at CROs, including contract initiation/execution, design of studies, study initiations, study monitoring ensuring study quality, and supporting the delivery of study reports in a timely fashion
  • Design, develop and execute studies independently and in collaboration with team members
  • Generate PK-PD-biomarker correlations that help bridge the in vivo pharmacology/toxicology data to PK and efficacy
  • Interpret and report biomarker data to project teams and management to enable and drive project decisions
  • Generate relevant reports and archive appropriate documentation

Requirements

  • Ph.D. in Immunology, Cancer Biology or related field.
  • Minimum of 7 years of experience within the Pharmaceutical/Biotechnology sector.
  • Experience with the discovery, characterization, clinical validation and utilization of innovative biomarkers.
  • Strong scientific skills and prior experience implementing biomarkers in clinical studies.
  • Direct experience in development, outsourcing and validation of clinically applicable biomarker assays is required.
  • Excellent verbal, written and problem solving skills are required.
  • Expertise in one or more of the following therapeutic areas is desired: oncology, nephrology, inflammation.
  • Excellent track record of working in teams, leading teams, record-keeping, and organization skills.
  • The successful candidate will enjoy working as a member of a fast-paced multidisciplinary project team in an entrepreneurial environment.

Reference Job Code: #021

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Scientist I, Chemistry (Multiple Positions)

We seek highly motivated, hands-on professionals to augment the medicinal chemistry and/or chemistry development research teams to design and safely carry out the synthesis and purification of drug candidates on milligram to kilogram scales for drug candidate discovery and development.

Responsibilities

In this position, you will make significant contributions to understanding scientific issues and/or to solving scientific problems by applying organic/physical chemistry principles. You will synthesize and characterize novel molecules, identify structure-property relationships in terms of potency, selectivity, and pharmacokinetics and use the information gained to further optimize compound properties. Mature projects may involve chemistry optimization towards commercialization routes. You will interact and maintain productive relationships with project team members in all departments: chemistry, biology, DMPK, and external collaborators. You may supervise Research Associates and contribute to their professional development.

Requirements

  • Ph.D. in chemistry, with a strong background in organic synthesis (postdoc experience is a plus).
  • Hands-on experience using modern chromatographic and spectroscopic techniques such as NMR, LC-MS and HPLC.
  • Demonstrated problem solving skills and productivity in organic synthesis and/or method development as evidenced by publications and/or patents.
  • Highly collaborative, self-motivated, team-oriented individuals with strong oral and written communication skills.

Reference Job Code: #033

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Senior Clinical Trial Manager

Reporting to the Chief Medical Officer, the Senior Clinical Trial Manager will be responsible for the day-to-day management of ChemoCentryx clinical trials, including management of contract CROs conducting company sponsored clinical trials.

Specific Responsibilities

  • Work with CROs to ensure that patient enrollment and data collection are completed in accordance with study timelines and objectives; escalates risk to timelines and budget as needed.
  • Work with CRO to revise scope of service agreements, budgets, plans and detailed timelines, and ensure that performance expectations are met.
  • Oversee monitoring activities at clinical CROs by reviewing visit reports, protocol deviations and CAPAs; attend co-monitoring visits as required.
  • Monitor study progress: ensuring compliance with relevant regulations and guidelines by maintaining regular contact with external vendors, including CRAs as applicable.
  • Review and contribute to study Protocols, eCRF design and completion guidelines, laboratory manuals, Informed Consent Forms, and other study-related documents.
  • Coordinate/plan investigator meetings and/or site and CRA training.
  • Perform financial management, including review and approval of site and vendor invoices.
  • Track and coordinate trial related materials, including clinical trial supplies and laboratory samples.
  • Perform review and QC central clinical files and trial master file.
  • Identify potential study issues and recommend and implement solutions or corrective actions as needed.
  • Serve as a liaison and resource for investigational sites; review investigator contracts and site payments.
  • Travel to CRO/vendor facilities and/or investigative sites to train and assess study team and CRAs.
  • Organize and manage internal team meetings and other trial-specific meetings.
  • Participating in the development, review and implementation of departmental SOPs and processes.

Qualifications

  • Baccalaureate or Masters degree or equivalent in a scientific or health care field is required.
  • Minimum of 3-5 years of clinical trial management experience, including CRO/vendor management, monitoring of budget scope, clinical site monitoring, and knowledge of basic data management/biostatistics processes and pharmacovigilance.
  • Experience in managing oncology clinical trials and/or orphan disease indications preferred.
  • In-depth knowledge of clinical research operations, including interpretation and implementation of FDA regulations/ICH guidelines, GCP and other applicable regulatory guidelines required.
  • Knowledge of Electronic Data Capture (EDC).
  • Excellent verbal and written communication skills in order to effectively communicate with site staff, vendors and internal cross functional team members.
  • Strong computer skills including knowledge of Microsoft Excel, Word, and Outlook.
  • Ability to work within established timelines, in a fast paced environment.
  • Excellent organizational and priority management skills.
  • Ability to prioritize and handle multiple tasks at once.
  • Travel up to 15-20% may be required.

Reference Job Code: #031

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