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ChemoCentryx, a pharmaceutical company located in Mountain View, CA, seeks highly motivated professionals to join our team.

All ChemoCentryx employees share the rewards of their work through a generous stock option program. We also offer 401K and Flexible Spending Accounts, and a comprehensive benefits package, including medical, dental and vision coverage and life and long-term disability insurance.

Please email your resume & cover letter to: hiring@chemocentryx.com or FAX to: (650) 210-2910. No phone calls please. EOE


Associate Medical Director - Medical/Clinical Affairs

This Associate Medical Director level position requires the ability to work with supervision, in responsibilities associated with all aspects of design, setup, monitoring, and analysis of Phase 1 - 3 clinical trials. This person must have the ability to interact effectively with other members of the department, as well as with study investigators and their staff, CROs and vendors operating on behalf of ChemoCentryx. The individual is this position will also be required to be involved in other duties in the department including strategic planning, clinical plan development, potential partnering discussions, departmental meetings, planning and preparation for scientific meetings, staff training, and patient recruitment initiatives.

Responsibilities

  • Co-lead the CCX168 and CCX140-B clinical development programs in ANCA-associated glomerulonephritis and diabetic nephropathy, respectively; as such, participate in investigator outreach activities, design, placement, execution, data analysis, and report writing for the clinical trials, including Phase 1, Phase 2, and Phase 3 clinical trials.
  • Medical monitoring of active clinical trials in the CCR2, C5aR, and CCR9 antagonist programs.
  • Lead specific clinical trials, e.g., CCX168 Phase 1 and later stage clinical trials.
  • Attend scientific meetings on behalf of CCXI to meet with investigators and key opinion leaders, submit and present abstracts.
  • Organize and lead scientific advisory board meetings.
  • Be actively involved in planning and preparation of Regulatory meetings and submissions, e.g., CCX168 End-of-Phase 2 meeting.
  • Help mentor and guide other Department members.
  • Participation in generation and critical review of study-related documents including study protocols, protocol amendments, investigator brochures, monitoring plans, informed consent documents, and CRFs.
  • Includes travel up to 30% at times.

Education & Experience

Requires an MD with a minimum of 1 year of industry experience. Experience in one or more of the following area(s): Nephrology, rheumatology, internal medicine, or endocrinology desirable. Prior training and experience with Good Clinical Practices (GCPs). Excellent verbal and written skills along with the ability to work collaboratively in a dynamic and creative environment. Track record of creativity, high performance, and demonstrated ability to work independently and meet deadlines. Exhibits initiative, is proactive and able to contribute to overall medical and clinical development activities. This position requires attention to detail and the ability to interact effectively with other staff.

Reference Job Code: #012

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Director - Human Resources

Seeking Human Resources Director to manage the planning and implementation of HR strategies, programs, and initiatives to support the achievement of the company's short and long-term business objectives.

Some of the Key Responsibilities

  • Partners with managers and senior management in all matters concerning Human Resources and People Management
  • Develops annual HR Strategic Plan in conjunction with senior management
  • Drives delivery of HR programs into the organization, including talent acquisition, staffing and selection, employment onboarding, compensation, training and development, talent management and succession planning, employee relations, AA/EEO compliance, and retention
  • Helps to drive organizational effectiveness through Performance Management processes; improves manager and employee performance by identifying problems; evaluating, and implementing recommended solutions; coaching and counseling managers and employees. Assists with the delivery of training when needed
  • Consults with department heads & senior management on organizational structures that will support and enable talent management, employee development, and building of capabilities to support the company's vision and strategic goals

Requirements

  • Ability to foster a positive team environment and build trusting relationships with employees
  • Track record of success in achieving results
  • Demonstrated success providing direct, complete, and actionable corrective feedback
  • Effective communicator -- strong presentation and public speaking skills; able to write clear and succinct messages for a myriad of purposes and audiences
  • Comfortable in fast-paced and dynamic organizations
  • Experience in employee relations and performance management

Education and Experience

Bachelor's degree or equivalent, plus a minimum of 10 years progressively responsible HR experience. Experience in the Biopharmaceutical Industry highly desired.

Reference Job Code: CCX #017

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Director/Sr. Director - Pharmaceutical Development

This position requires the ability to work independently, in responsibilities associated with all aspects of chemistry, manufacturing and controls (CMC) for ChemoCentryx drug candidates. This person must have the ability to interact effectively with other members of the department, as well as with Regulatory agencies, consultants, and external vendors operating on behalf of ChemoCentryx. The individual is this position will also be required to be involved in other duties in the department including strategic planning, potential partnering discussions, departmental meetings, planning and preparation for consultant and Regulatory meetings, and staff training.

Responsibilities

  • Oversees and directs all chemistry, manufacturing and controls (CMC) regulatory and manufacturing strategies for new products.
  • Provides guidance and support to internal pharmaceutical development personnel as well as to outside groups such as contract manufacturing organizations to ensure that products are manufactured in compliance with all applicable regulations.
  • Provides strategic input and risk assessments and oversees preparation of CMC regulatory submissions.
  • Interacts with regulatory agencies.
  • Selects, develops and evaluates personnel to ensure the efficient operation of the function.
  • Directs the design and scale-up of processes, instruments and equipment from the laboratory through pilot plant and manufacturing scale-up.
  • Manages the development, implementation and maintenance of process methods and equipment for the production of process formulas, technologies and products to achieve cost effectiveness and product quality.
  • Plans and implements the development of new process formulas, establishes operating equipment specifications and may improve manufacturing techniques and new process equipment production.
  • Acts as liaison with research and/or development to ensure processes and designs are compatible.
  • Selects, develops and evaluates personnel to ensure the efficient operation of the function.

Education & Experience

Requires a PhD in a relevant field with a minimum of 5 years of industry experience. Prior training and experience with Good Manufacturing Practices (GMPs). Excellent verbal and written skills along with the ability to work collaboratively in a dynamic and creative environment. Track record of creativity, high performance, and demonstrated ability to work independently and meet deadlines. Exhibits initiative, is proactive and able to contribute to overall CMC activities. This position requires attention to detail and the ability to interact effectively with other staff. Level of position will be commensurate with level of experience.

Reference Job Code: #015

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Research Assistant/Associate - Biology (6 month temporary assignment)

As a member of the lead discovery and optimization group, your primary responsibility will be to develop high-quality antagonist that advance into preclinical development by providing high-quality biological data using a combination of in vitro biochemical and cell culture assays, including cell migration, radioligand binding and cytoplasmic calcium flux assays. Speed, quality and communication are essential skills for this position. In addition, handling and tracking novel compounds, growing mammalian cells in sterile tissue culture, handling laboratory robotics, maintaining accurate and complete records in a laboratory notebook, and being responsible for entering results into an Oracle database are required.

Basic requirements include a BS degree in biological sciences. Preferred qualifications include a MS and/or 1 to 2 years' experience in pharmacology or drug optimization.

Reference Job Code: #T001

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Scientist/Sr. Scientist - Biology

We currently seek a Scientist to join our Biology Group. The position requires a Ph.D. in Immunology, Cancer Biology or related field, with strong history of publication in top tier scientific. The title is flexible (Scientist - Sr. Scientist) and will be commensurate with the candidate's background and experience.

The successful candidate will have the following primary responsibilities:

  • Lead independent research efforts into the basic biological functions of the chemokine/chemo-attractant receptor system(s)
  • Provide internal and external presentations/publications to articulate research results, milestones, challenges, and plans

Requirements

  • The successful candidates will have a PhD in Immunology, Cancer Biology or related field and have completed postdoctoral training. Minimum of 2 years' experience in the biopharmaceutical industry required.
  • Experience with in vivo biological models preferred.
  • Experience in multi-color flow cytometry necessary.
  • Strong molecular biology experience is a plus.
  • Experience in immunohistochemistry and tissue culture is desired.
  • Previous experience of working with human cells/tissues is a plus.
  • Excellent verbal, written and problem solving skills are required.
  • Proven track record of publication in high impact scientific journals required
  • The successful candidate will enjoy working as a member of a fast-paced multidisciplinary project team in an entrepreneurial environment.

Reference Job Code: CCX#14

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Sr. Associate Scientist/Scientist - Biology

As a member of the molecular pharmacology group, you will be responsible for developing and performing a variety of cell-based in vitro assays supporting novel therapeutic development programs. The position requires solid cell culture skills and the ability to conduct reproducible cell-based assays. Attention to detail, strong communication skills, and the ability to work both independently and as part of a team is essential for this position. Experience with in vivo models and/or biomarkers a plus.

Minimal educational requirements include an MS degree in a biological science with 3+ years, or a BS degree with 5+ years of relevant experience. Preferred candidates will have extensive experience in Multi-color flow cytometry.

Reference Job Code: CCX#016

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