Join Our Team.

We seek highly motivated professionals to join our team. We invite you to schedule a visit through Human Resources to learn more about our company and see our current open job postings below.

We participate in E-Verify, the US Government sponsored right-to-work verification process.

Administrative

Position Overview

Our Administrative Assistants are the glue that keeps our team together and the driving force that keeps our business moving forward.  Reporting directly to the Head of Pharmaceutics, the Administrative Assistant will be part of an impactful group that keeps our executives well supported.  In this role, you will handle a variety of professional assistance responsibilities to support the Head of Pharmaceutics and other members of the senior management team.

This role requires a strong attention to detail, lots of flexibility, keen insight and resourcefulness, and the ability to juggle projects with aggressive deadlines.  This position requires a rapid pace, clear communications, a high level of discretion, critical thinking and impeccable judgement in handling sensitive and confidential information with advanced organizational and prioritization skills necessary for multitasking and keeping the Head of Pharmaceutics and senior management team members on track, on time, and informed in real-time.

Essential Duties and Responsibilities

  • Support Vice President-level Senior Management Team Members with calendaring, meeting prioritization, planning and coordinating off-site meetings and team events, booking travel and accommodations; attending team meetings as requested, and other tasks as assigned by the Executive(s)
  • Maintain confidential files and contact information, process expense reports, ensure contracts and agreements are executed and routed appropriately.
  • Provide coverage and support to other group administrators and partners with other support functions
  • Responsible for organization and maintenance of reception area and conference rooms with other group administrators
  • Prioritize conflicting needs; handles matters expeditiously, proactively, often with deadline pressures.
  • Presence in the office Monday through Friday, with the willingness to respond after hours and on weekends as needed

Requirements

  • High School education required; Bachelor’s Degree highly preferred
  • Typically requires a minimum of 2+ year’s general administrative experience, or equivalent combination of experience and college level education.
  • Proficient in Microsoft Office (Outlook, Word, Excel, and Power Point), Adobe Acrobat
  • Be a trusted partner, maintaining confidentiality and professionalism in all situations.
  • Proven success building and maintaining relationships of trust, respect, and support with other administrative assistants
  • Demonstrated poise, tact, and confidence when dealing with executives at the highest level in the company
  • Discretion, diplomacy and excellent judgment; high degree of integrity when dealing with confidential and sensitive information
  • Independent professional with strong analytical skills with ability to make critical decisions with limited guidance in support of Head of Pharmaceutics and other executives
  • Strong verbal and written communication skills to interface with internal and external partners
  • Be detail-oriented with high attention to detail, organization, and process
  • Approachable, resourceful, a creative problem-solver, quick on your feet, out-of-the-box thinker
  • Resilient, ability to manage multiple projects and deliver quality work to deadlines

Preferred Experience

  • Supporting VP / SVP / C-Level Executives in a fast-paced and dynamic environment a plus

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form I-9 process.  www.dhs.gov/E-Verify.

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Position Overview

Our Administrative Assistants are the glue that keeps our team together and the driving force that keeps our business moving forward.  Reporting directly to the Senior Vice President, Head of Commercial, the Executive Assistant will be part of an impactful group that keeps our executives well supported.  In this role, you will handle a variety of professional assistance responsibilities to support the Senior Vice President, Head of Commercial and other members of the senior management team.

This role requires a strong attention to detail, lots of flexibility, keen insight and resourcefulness, and the ability to juggle projects with aggressive deadlines.  This position requires a rapid pace, clear communications, a high level of discretion, critical thinking and impeccable judgement in handling sensitive and confidential information with advanced organizational and prioritization skills necessary for multitasking and keeping the Senior Vice President, Head of Commercial and senior management team members on track, on time, and informed in real-time.

Essential Duties and Responsibilities

  • Support Vice President-level Senior Management Team Members with calendaring, meeting prioritization, planning and coordinating off-site meetings and team events, booking travel and accommodations; attending team meetings as requested, assisting with clinical filings, and other tasks as assigned by the Executive(s)
  • Maintain confidential files and contact information, process expense reports, ensure contracts and agreements are executed and routed appropriately.
  • Provide coverage and support to other group administrators and partners with other support functions
  • Responsible for organization and maintenance of reception area, conference rooms and office supply room with other group administrators
  • Prioritize conflicting needs; handles matters expeditiously, proactively, often with deadline pressures.
  • Presence in the office Monday through Friday, with the willingness to respond after hours and on weekends as needed

Requirements

  • High School education required; Bachelor’s Degree highly preferred
  • Typically requires a minimum of 5+ year’s general administrative experience, or equivalent combination of experience and college level education.
  • Proficient in Microsoft Office (Outlook, Word, Excel, and Power Point), Adobe Acrobat
  • Be a trusted partner, maintaining confidentiality and professionalism in all situations.
  • Proven success building and maintaining relationships of trust, respect, and support with other administrative assistants
  • Demonstrated poise, tact, and confidence when dealing with executives at the highest level in the company
  • Discretion, diplomacy and excellent judgment; high degree of integrity when dealing with confidential and sensitive information
  • Independent professional with strong analytical skills with ability to make critical decisions with limited guidance in support of Senior Vice President, Head of Commercial and other executives
  • Strong verbal and written communication skills to interface with internal and external partners
  • Be detail-oriented with high attention to detail, organization, and process
  • Approachable, resourceful, a creative problem-solver, quick on your feet, out-of-the-box thinker
  • Resilient, ability to manage multiple projects and deliver quality work to deadlines

Preferred Experience

  • Supporting VP / SVP / C-Level Executives in a fast-paced and dynamic environment a plus

We participate in E-Verify, the US Government sponsored right-to-work verification process.

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ChemoCentryx is looking for an ambassador to candidates, new hires and existing employees. This is a great opportunity for someone with a passion for people, organization, and community. Playing a key tactical role throughout the employee lifecycle from hiring and on boarding to developing and off-boarding, this individual will deliver on operational excellence while maintaining high levels of confidentiality. To be successful in this role, this individual must have a process improvement mindset and confidently take ownership for driving all day-to-day HR operations.

What You’ll Do

  • Primary HR contact for ChemoCentryx employees, responsible for answering questions and solving day-to-day problems for the organization accurately and in a timely manner
  • Represent the recruiting team internally and externally, acting as an ambassador to candidates, fostering an overall positive candidate experience at ChemoCentryx
  • Assist in building and maintaining a sourcing pipeline and candidate pool via networking, partnerships, research and social media tools
  • Schedule interviews, coordinate travel arrangements and expense reimbursement as needed, and meet and greet candidates who arrive for interviews
  • Coordinate pre-hire activities including drafting and circulating offer letters, background checks, drug screening, onboarding and sending out new hire paperwork; Process l-9s/E-Verify, conduct new hire orientations and address benefits/perks questions
  • First point of contact for employee benefit issues
  • Support administration of Leaves of Absence (FMLA/CFRA, PDL, Disability)
  • Process personnel changes (acquire proper approvals, perform data entry, ensure changes are reflected in applicable internal systems)
  • Off board employees/contractors by getting their departure paperwork prepared and assisting in the exit interview
  • Create a consistent, positive work atmosphere through the communication and administration of HR policies and procedures
  • Provide support for all HR programs and initiatives including benefits open enrollment, employee engagement initiatives, training, performance management and company events
  • Maintain and organize employee facing resources – ensuring forms, policies and resources are up-to-date and easily accessible by employees
  • Maintain and provide reports (staffing reports, headcount reports, org chart, demographics, etc.)
  • Maintain and update HR data and personnel files
  • Identify and drive process improvement efforts, leveraging systems and tools to automate and eliminate manual work where possible

Who You Are

  • Flexible, fearless, and excited about your part in our growth
  • You like to take on new challenges and don’t wait to be told to get started on something
  • Proactive resourcefulness and initiative to ask questions coupled with the ability to self-manage work
  • A utility player. You’re willing to help wherever needed with a client service mindset
  • Great sense of humor

What We Look For

  • Bachelor’s Degree required
  • 2+ years of related internship/work experience in HR or Talent Acquisition
  • Experience in recruiting and scheduling, experience recruiting in biotech, pharma industries a plus
  • aPHR or similar certification is an advantage
  • Broad knowledge of HR principles and best practices
  • Basic knowledge of California and federal labor law (FMLA/CFRA, ERISA, wage and hour, EEO, OFCCP, ADA, employment/immigration laws, etc.) preferred
  • Proficient in MS Office
  • Working knowledge of HR systems, benefits plans and payroll processes preferred
  • Exceptional people skills. Strong verbal, written, and interpersonal communication skills are a must.
  • A high level of discretion and the ability to appropriately manage confidential information
  • Outstanding follow-through, self-directed and highly motivated with a strong sense of urgency
  • Meticulous attention to detail.
  • Genuine team player with an interest in building community and authentic relationships

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 197 4, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form 1-9 process. www.dhs.gov/E-Verify.

To all recruitment agencies: ChemoCentryx, Inc. does not accept unsolicited agency resumes and will not be responsible for the payment of placement fees related to unsolicited resumes submitted to open positions, job aliases, or to our employees.

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Finance and Accounting

Job Objective

Responsible for all financial reporting and compliance functions, including but not
limited to, internal financial and SEC regulatory reporting.

Principal Duties and Responsibilities:

  • Responsible for all external financial reporting, including quarterly and annual regulatory filings and other required filings with the Securities and Exchange Commission.
  • Responsible for concurrent filing of XBRL exhibits with quarterly reports (Form 10-Q) and annual reports (Form 10-K).
  • Responsible for clinical trial accruals for all clinical operations. Ensure timely analysis and account reconciliation, including preparation of monthly journal entries to the general ledger.
  • Responsible for recording collaboration and grant revenue, including research and development funding from our collaboration partner.
  • Responsible for project expense reporting.
  • Sustain Company’s Sarbanes-Oxley Section 404 compliance efforts with respect to SEC Reporting, related monthly close and other activities.
  • Perform special projects and other analytical support as requested.

Job Scope
Works with all employees to assist in financial accounting matters.

Interaction (level of positions, nature of interaction, frequency):

Internal Contacts:
Regularly interacts with company leaders and other employees regarding finance and accounting related matters.

External Contacts:
Regularly interacts with external auditors (government and corporate) and vendors.

Amount of Supervision Received:
Requires minimal-to-moderate level of supervision. Minimum supervision on routine matters, moderate supervision on more complex
matters.

Specifications
Education: BA/BS in Accounting/Finance.

Experience: 5-7 years related financial accounting experience. CPA with “big four” experience and/or public biotechnology or biopharmaceutical company experience preferred.

Skills and Capabilities: (Specific abilities needed for the position)

  • Energetic, flexible team player and hands-on leader with the ability to manage in a dynamic environment. Diplomatic yet effective in garnering respect and cooperation from management of other function areas.
  • Strong attention to details and accuracy.
  • Strong problem solving skills.
  • Excellent written and oral communication skills, including ability to communicate effectively with external parties and all levels of staff in a timely fashion.
  • Time management and organizational skills. Ability to multi-task and effectively prioritize.
  • Proficiency with MS Excel, Word, PowerPoint and Great Plains

We participate in E-Verify, the US Government sponsored right-to-work verification process.

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Medical Affairs

Position Overview

As VP, Medical Affairs, you will build and lead a headquarters and field-based medical team that will launch Avacopan, a truly innovative and disruptive product for AAV. You will lead development and execution of a medical launch plan that will shift the treatment paradigm for people living with AAV. Beyond launch, you will provide medical and scientific leadership to unleash the full potential of Avacopan and other CCXI drugs in development to make a difference for patients. Your leadership will be essential in making this vision for Avacopan into a new reality for the AAV community.

Essential Duties and Responsibilities

  • Recruit and lead top-tier medical affairs talent to serve as leaders and members of the Avacopan Brand Medical Affairs Team and Field Medical Affairs Team
  • Develop and execute a comprehensive Avacopan Medical Launch Plan that is aligned with the overarching brand plan
  • Build a high-impact medical and scientific platform, including: scientific exchange and partnership with KOLs, medical communication and publication plans, scientific congress activities, medical education programs, scientific advisory boards and a post-approval evidence generation plan (LCM)
  • Be a “medical voice” and “scientific mind” on the cross-functional brand team, in close partnership and collaboration with the brand champion
  • Ensure all activities are conducted with the highest levels of scientific rigor and in full compliance with applicable rules and regulations
  • Create an energetic, positive, performance-based culture with the Brand Medical Affairs Team and Field Medical Affairs Team that is aligned with the overall ChemoCentryx culture and supports the growth and professional development of every team member

Requirements

  • Have a board-certified MD or PhD, with clinical trial experience; a graduate degree in business management, health policy or healthcare administration in addition to a medical degree is desirable
  • Have at least 10 years of medical affairs leadership experience in the pharmaceutical, biotechnology or medical device industry, preferable including headquarters and field experience
  • Have scientific knowledge and experience in the area of renal and/or autoimmune diseases. Alternatively, clearly demonstrated the ability to master a new therapeutic area deeply and quickly
  • Experience in the evolving healthcare system, with payers, IDNs or both
  • Successfully supported the launch of multiple transformative drugs or devices; preferably in the rare disease space
  • Strong and consistent track record of success, developing strategy and executing operational plans
  • Possess a strong understanding of medical management principals and experience with supporting data analytics focused on outcomes analysis and management
  • Preferably (not essential) have prior experience in a decision maker role in a startup life science company
  • Intimate understanding of the role of healthcare regulators and compliance
  • Have experience in handling media / PR issues
  • Have a strong network of influential relationships with key healthcare surgical stakeholders
  • Pragmatic business approach to problem solving
  • Be a confident and engaging presenter as part of the business team and to conference audiences
  • Understand the science and business of medicine, and can speak both languages
  • High level of emotional intelligence along with outstanding ability to lead and inspire others
  • Translate concepts and ideas into timely action and high-impact results; known for both innovation and execution
  • Uphold impeccable ethics and unquestionable integrity in all that you do
  • Known as both a strong team leader and cross-enterprise leader
  • Strong executive presence, able to communicate complex ideas with clarity and concision
  • High energy, collaborative spirit and an entrepreneurial mindset
  • Comfortable with ambiguity and uncertainty
  • Unwilling to settle for anything less than excellence in yourself and your team

The VP of Medical Affairs will possess the following competencies:

  • Business Acumen: Possess a thorough grasp of details and key business drivers in the health care industry and the organization where the most value can be obtained
  • Setting Strategy: An ability to develop and set the strategic vision using sound business judgment, independent thinking, while being able manage through ambiguity in this evolving health care delivery environment
  • Executing for Results: Accustomed to being accountable for driving results, committed to improving performance for the company and its clients, demonstrated tenacity and an ability to make timely decisions in difficult and ambiguous circumstances
  • Leading Teams: Experience recruiting high caliber individuals and teams and managing performance while leveraging diversity and strengths of individuals
  • Building Relationships and Using Influence: An ability to develop and leverage key relationships by building commitment, selling ideas and communicating clearly and persuasively
  • Motivation: VP of Medical Affairs will be competitive, entrepreneurial and achievement driven for the good of the organization and able to work well in collaboration with others

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form I-9 process.  www.dhs.gov/E-Verify.

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Marketing

Position Overview

The Vice President, Market Access will lead the company’s efforts of securing optimal patient access and reimbursement for the company’s products with near term focus on ChemoCentryx’s lead compound avacopan for patients with ANCA-associated Vasculitis. S/he will be responsible for creating and leading the execution of the foundational market access, reimbursement and distribution strategy and plan. This will include pricing, contracting and reimbursement strategy, channel management and contract operations, patient services and market access operations. This position reports to the SVP, Head of Commercial and will work closely with Medical Affairs and the commercial and finance teams.

Essential Duties and Responsibilities

  • Build and  deploy  the  Market  Access  Strategy  and  integrated  policy  and  communications approaches to optimize patient access for ChemoCentryx therapies
  • Develop, lead and execute access, reimbursement and distribution strategy for our lead asset
  • Collaborate on the development of optimal pricing strategies and oversee implementation of pricing activities consistent with the strategy
  • Work closely with Sales, Marketing, Medical Affairs, and Legal to develop and execute integrated product access plans to ensure affordable, timely coverage
  • Plan and implement distribution strategies including 3PL, Wholesalers and Specialty Pharmacy networks.
  • Plan and design patient support programs to optimize access to ChemoCentryx products.
  • Establish and drive  key  performance  metrics,  build  dashboards,  analyze  performance  and recommend actions to resolve barriers to drug access
  • Bring an understanding of the payer perspective to product core teams to ensure that payer requirements are adequately met throughout the evidence development and commercial strategy development processes in a timely and accurate fashion
  • Provide expert view  on  the  Pricing  and  Reimbursement  system and  evolving  public  policy environment and competitive access landscapes to inform corporate strategy and long-range planning
  • Oversee training of cross-functional stakeholders to educate on key market access initiatives, messaging and materials
  • Collaborate with Finance, Legal, and other functions to establish consistent business rules and policies focused on appropriate and compliant reporting and ensure all Market Access activities comply with regulatory agencies, public policies/guidelines, and with corporate policies and procedures
  • Work with Medical Affairs to conduct HEOR data and analysis to enable the development of the value dossier
  • Attract, hire and lead a high performing market access team to ensure launch readiness ahead of upcoming launches

Requirements

  • Bachelor’s or Master’s degree; MBA preferred
  • 12+ years in the biopharmaceutical industry, with at least 5 years specifically in market access
  • Proven track record in pricing, reimbursement and market access
  • Experience successfully launching new products, achieving formulary access and market share objectives; Rare disease therapeutic experience a plus
  • Hub, field reimbursement and government pricing experience
  • Successful track record in engaging public and private payers, specialty societies, and other key stakeholders
  • Extensive knowledge of reimbursement terminology, managed care and healthcare policy, including comprehensive understanding of standard managed contract language
  • Demonstrated success building organizations, creating and leading high performing teams
  • Strong understanding of legal and regulatory environment  in pharmaceutical promotions,  pharma industry guidelines, and other compliance-related  issues
  • Ability to assess risks and benefits to make timely, sound decisions with various levels of information, and accept responsibly for meeting and/ or exceeding objectives
  • Problem solving orientation with strong strategic and analytical abilities, diplomacy, negotiation and excellent oral and written communication skills
  • Ability to communicate complex information in a convincing  way to non-technical audiences
  • Ability to work in a fast-moving, dynamic small-company environment
  • Ability to tr vel approximately  40% of the time

We participate in E-Verify, the US Government sponsored right-to-work verification process.

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Pharmaceutical Development

Essential Duties and Responsibilities

  • Responsible for development and overseeing timelines associated with manufacturing, release and distribution of clinical supplies including manufacturing, labeling development, approval and printing, labeling operation, release and distribution to clinical sites.
  • First line reviewer of all the clinical batch records supporting manufacturing, packaging and labeling operations performed by the CMO’s
  • Responsible for keeping up to date the Clinical Supplies requests generated by Clinical Development for all programs and provide prompt feedback on the plans for delivery
  • Responsible to maintain an accurate inventory of Clinical Supplies at the CMO’s: Drug Substance, Drug Product
  • Responsible for tracking the manufacturing, packaging and labeling of clinical supplies and provide weekly updates to the Executive Director of PD and the appropriate Program Manager
  • Working with other members of the PD team ensure that shipping conditions for all clinical supplies materials (drug substance and drug product) are developed and maintained according to Good Distribution Practices
  • Serve as a liaison between CMO and Clinical Operations regarding clinical supplies requests, deliverables and distribution of clinical supplies from manufacturers to global warehouses and distribution centers.
  • Working closely with Quality, ensure that labels are created following the cGMP and cGCP practices
  • Serve as the point of contact between Clinical Operations and PD regarding the drafting, approval and manufacturing of labels for clinical supplies
  • Serve as the point of contact between Clinical Operations and PD regarding the drafting, approval and manufacturing of kits and secondary packaging for clinical supplies
  • Responsible for tracking re-test dates for all clinical supplies and making provisions for the extension of the re-test dates as appropriate
  • Maintain up to date the specifications for all clinical materials used in the clinic according to latest IMPD/IND updates
  • Responsible for the managing requests to proposal associated with the clinical supplies packaging, labeling and distribution of clinical supplies
  • Maintain a monthly tracking document regarding clinical supplies expenses incurred against approved contracts
  • Manage and track change orders and make sure that internal authorizations are received in a timely manner
  • Respond to finance on questions regarding charges, P.O.’s , and contract regarding Clinical Supplies CMO’s

 

 

 

Requirements

  • Requires a Bachelor’s degree and highly preferable in a science-related field; MS, PharmD, or PhD desirable.
  • 10+ years of progressively responsible experience in the pharmaceutical industry, 7+ of those years include technical and direct product development experience for late stage Product Development and during product commercialization
  • Candidate should be considered an expert in late stage small molecules product development with proven technical experience in one or more of the following areas: Process Chemistry and manufacturing scale-up for drug substance, analytical method development for drug substance and drug product formulation and manufacturing process for Phase III and commercial drug product.
  • Proven experience as it relates to managing and interaction with CMO’s from early through late drug product development
  • Program Management skills highly desired.
  • Experience in authoring CTD sections as they relate to drug substance, drug product, analytical chemistry and specification settings in support of IND’s, NDA’s, MAA’s and IMPD’s
  • Deep knowledge of the GMP regulations requirements in product development manufacturing and release of clinical and commercial products
  • Proven track record in strategic planning for late stage development programs. Commercial experience highly desired.
  • Must have strong regulatory compliance working knowledge including FDA, cGXP, etc.
  • Must be detail oriented with excellent prioritization, organizational and project management skills.
  • Superior analytical and problem solving skills.
  • Effective communication (written and verbal) skills.
  • Ability to travel up to 30%

We participate in E-Verify, the US Government sponsored right-to-work verification process.

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Research

Position Overview

The Head of Biology will report to the President and will be a highly motivated immunologist, inflammation biologist, or immune-oncology expert who will participate in and drive the discovery and advancement of novel therapeutics for the treatment of inflammatory diseases and cancer. This life sciences research leader will be immersed in the strategic development and implementation of early and late stage research programs while identifying new targets to ensure that a robust pipeline of product candidates is moving towards the clinic. This person will work closely with the members of the executive team and provide both strategic and day-to-day guidance to the scientific team.

Essential Duties and Responsibilities

Primary responsibilities will be to lead and support drug discovery and to investigate the mechanism of action of clinical development compounds and candidate lead molecules. The successful candidate will be expected to independently design, execute and manage internal research projects, collaborate with other functional groups within the broader organization and manage external collaborations. In addition, the candidate will contribute to patent filings and publications and present research finding to various audiences including senior management.

Requirements

  • D. in Biology, Immunology, or related discipline
  • 10+ years of industry experience in small molecule drug discovery/development, with at least 5 years in a leadership role
  • Evidence of scientific leadership with publication in top-tier journals
  • A successful track record of advancing multiple product candidates from discovery to the clinic, with lead responsibilities
  • Prior experience and training in Immunology and Immuno-Oncology
  • Direct experience with a broad range of immunological techniques, including isolation and stimulation of primary immune cells (of human and rodent origin), multi-color flow cytometry, immune cell-based assay development
  • Well-developed organizational, creative problem solving and collaborative skills
  • Must be self-motivated and proactive, able to multi-task, and detail oriented
  • Strong verbal and written communication skills, as well as effective listening and interpersonal skills

Preferred Experience

  • Prior experience working with inflammation models to elucidate mechanisms and mediators of disease and therapeutic efficacy and/or drug mechanism of action is highly desirable
  • Prior experience in biotherapeutic discovery and preclinical development, together with a strong understanding of ligand-receptor biology is highly desirable
  • In depth expertise in human immunology is highly desirable

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form I-9 process.  www.dhs.gov/E-Verify.
To all recruitment agencies: ChemoCentryx, Inc. does not accept unsolicited agency resumes and will not be responsible for the payment of placement fees related to unsolicited resumes submitted to open positions, job aliases, or to our employees. 
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As a member of the lead discovery and optimization group, your primary responsibility will be to develop high-quality antagonist that advance into preclinical development by providing high-quality biological data using a combination of in vitro biochemical and cell culture assays, including cell migration, radioligand binding and cytoplasmic calcium flux assays. Speed, quality and communication are essential skills for this position. In addition, handling and tracking novel compounds, growing mammalian cells in sterile tissue culture, handling laboratory robotics, maintaining accurate and complete records in a laboratory notebook, and being responsible for entering results into an Oracle database are required.

Responsibilities

  • Performing research and development experiments for projects and products in collaboration with others.
  • With guidance, design and execute complex analytical and characterization work.
  • Make detailed observations, maintain laboratory notebooks, and help analyze data, and interpret results.
  • May help prepare technical reports and SOP’s covering procedures.

Requirements

  • BS in biological sciences required.

Preferred Experience

  • MS and/or 2 to 5 years experience in pharmacology or drug optimization.

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form I-9 process.  www.dhs.gov/E-Verify.

Submit Resume
ChemoCentryx is offering a unique opportunity for a highly motivated researcher to join our team, which is focused on the discovery and development of orally, parenteral and topical administered therapeutics to treat autoimmune diseases, inflammatory disorders and cancer. The ideal candidate will have significant experience in small molecule formulation preparation and development.

The primary role of this position is to provide pharmaceutics support for the development and preparation of formulations for new chemical entities from pre-clinical to IND and to advanced clinical development in Phase 2 and 3.

Responsibilities:

  • Design and conduct pre-formulation assessment studies of various novel drug candidates
  • Responsible for the development and evaluation of oral and parenteral dosage forms primarily in support of pre-clinical studies
  • The successful candidate will be responsible for preparation and timely delivery of formulations in support of efficacy, pharmacokinetic, pharmacology and toxicology studies
  • Responsibilities include managing and supporting in-house stability studies
  • The successful candidate will be responsible for evaluation and developing prototypes in support of clinical studies in different oral dosage forms (such as powder-in-bottle, liquid suspension, modified release technologies and solubility-enhancing platform), as well as parenteral dosage forms
  • The successful candidate is expected to have strong hands-on experience on analytical testing methods for drug product
  • The candidate will have opportunity to support drug product technology transfer from in­ house “proof-of-concept” prototypes to CRO clinical manufacturing sites, serve as the technical representative during manufacturing operations and participate in technical troubleshooting, review manufacturing batch records and CMO summary reports
  • Responsible for maintaining accurate laboratory data records and expected to summarize data regularly
  • Maintaining good operating condition of equipment and observing safety laboratory guidelines
  • The successful candidate must be self-motivated and organized, enjoy scientific investigation and thinking, proactively identify issues, and develop solutions

Qualifications:

  • Ph.D. degree in a Pharmaceutics, Pharmacy or other related scientific discipline
  • Direct hands-on experience with HPLC, XRPD, DSC, TGA, light microscopy, particle-size distribution, density, and pH meter
  • Experience on diverse oral drug product manufacturing unit operations: granulation, spray drying, encapsulation, tableting, film-coating, lyophilization, and sterilization procedure
  • Experience on developing parenteral formulation
  • Experience on measuring kinetic and equilibrium solubility in different media
  • Solid knowledge on dissolution and disintegration testing for solid dosage form
  • Effective communication skills are important to interact with scientists in a highly interdisciplinary and collaborative research environment
  • Independent worker who is willing to take on new responsibility and to learn new skills
  • Good team player who is willing to listen and understand different specific formulation needs of discovery team members
  • Exceptional oral communication and writing skills

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form I-9 process.  www.dhs.gov/E-Verify.
To all recruitment agencies: ChemoCentryx, Inc. does not accept unsolicited agency resumes and will not be responsible for the payment of placement fees related to unsolicited resumes submitted to open positions, job aliases, or to our employees. 
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Position Overview

ChemoCentryx is seeking a highly talented and motivated scientist to join our small molecule drug discovery team.  The successful candidate with a deep passion for drug discovery and a track record of accomplishments will play a key role in building our expanding pipeline of promising therapeutics.

Essential Duties and Responsibilities:

  • As a lead scientist, establish project goals/scientific strategies and effectively drive the medicinal chemistry efforts to meet aggressive corporate timeline
  • Closely follow emerging results of biological testing, ADME characterization, and other lead profiling assays; conceive and execute new scientific strategies for the rapid optimization and improvement of key drug attributes
  • Proactively gain competitive intelligence using available resources and incorporate this knowledge into internal drug discovery programs
  • Regularly provide medicinal chemistry and project updates to a multidisciplinary drug discovery team and senior management
  • Maintain a high level of productivity in the laboratory as evidenced by consistently generating high-impact compounds
  • Lead and contribute to the writing of patent applications, study reports, and scientific publications
  • Position may involve management of direct reports, depending on level of experience

Requirements:

  • PhD in organic chemistry or equivalent with at least 3 years of medicinal chemistry experience in pharmaceutical industry
  • Extensive knowledge of synthetic organic chemistry and superior problem solving skills; experience in designing and executing multistep synthesis of complex organic molecules using modern techniques in organic chemistry
  • Solid understanding and application of pharmacology, PK/PD, and ADME concepts
  • Ability to independently identify and promptly resolve core project challenges by effectively utilizing available information and scientific expertise
  • Demonstrated success in lead optimization, structure-activity relationship analysis, and property-oriented drug design, leading to development candidate nomination
  • Enthusiastic, high energy, and collaborative team player with strong ability to build productive relationships with scientists in the chemistry department and other disciplines to enable high individual performance and team success
  • Exceptional oral communication and writing skills
  • Previous supervisory and project leading experience highly preferred

As an equal opportunity employer, ChemoCentryx, Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. For more information about equal employment opportunity protections, please view the ‘EEO is the Law’ poster.

In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact careers@chemocentryx.com for assistance.

ChemoCentryx, Inc. is enrolled in E-Verify® and participates in E-Verify® in addition to our Form I-9 process.  www.dhs.gov/E-Verify.

Submit Resume